---
id: "refseq_accession"
kind: "datatype"
status: "draft"
is_pii: false
categories: ["science"]
langs: ["common"]
quality: 85
url: "http://registry.apicrafter.io/datatype/refseq_accession"
---

# NCBI RefSeq accession (`refseq_accession`)

> **Draft.** Draft records have not been reviewed yet and may be incomplete or wrong; do not treat them as authoritative for legal or compliance decisions.

Accession of a record in RefSeq, the curated, non-redundant collection of reference genomic, transcript and protein sequences of the US National Center for Biotechnology Information (NCBI). Two letters and an underscore give the kind of molecule, for example NM_ for an mRNA, NP_ for a protein and NC_ for a complete genomic molecule, and digits follow. A version such as .6 may be added; it grows when the sequence changes. Genome records of whole-genome shotgun projects start with NZ_ and a letter code. GenBank, ENA and DDBJ accessions without an underscore are a separate datatype (insdc_accession).

- Personal data (PII): no
- Categories: Scientific (science)
- Countries: global
- Languages: Common to most languages (common)
- Classification: identifier

## Detection

Regular expression (Python `re`):

```
^(((AC|AP|NC|NG|NM|NP|NR|NT|NW|WP|XM|XP|XR|YP|ZP)_\d+)|(NZ_[A-Z]{2,4}\d+))(\.\d+)?$
```

## Examples

- `NP_012345` — 40S ribosomal protein uS8 (RPS22A) of Saccharomyces cerevisiae; Bioregistry example
- `NM_000546.6` — Human TP53 mRNA, transcript variant 1, with its version
- `NM000546` (invalid example) — No underscore after the molecule code

## Mappings

- bioregistry: `refseq`

## Sources

- doc: <https://www.ncbi.nlm.nih.gov/refseq/>
- other: <https://bioregistry.io/registry/refseq>

## Quality

Score 85/100. Missing: translation, detector coverage.

JSON: <http://registry.apicrafter.io/api/v1/datatypes/refseq_accession.json> · Edit: <https://github.com/apicrafter/metacrafter-registry/edit/main/data/datatypes/any/science/refseq_accession.yaml>